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Outdoor air pollution and infant mortality: analysis of daily time-series data in 10 English cities

¹ London School of Hygiene & Tropical Medicine, London, UK
² University of Ulster, Newtownabbey, Co Antrim, UK

Correspondence to:
Correspondence to:
DrS Hajat
Public & Environmental Health Research Unit, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK; shakoor.hajat{at}lshtm.ac.uk

Background: There is growing concern that moderate levels of outdoor air pollution may be associated with infant mortality, representing substantial loss of life-years. To date, there has been no investigation of the effects of outdoor pollution on infant mortality in the UK.

Methods: Daily time-series data of air pollution and all infant deaths between 1990 and 2000 in 10 major cities of England: Birmingham, Bristol, Leeds, Liverpool, London, Manchester, Middlesbrough, Newcastle, Nottingham and Sheffield, were analysed. City-specific estimates were pooled across cities in a fixed-effects meta-regression to provide a mean estimate.

Results: Few associations were observed between infant deaths and most pollutants studied. The exception was sulphur dioxide (SO2), of which a 10 µg/m³ increase was associated with a RR of 1.02 (95% CI 1.01 to 1.04) in all infant deaths. The effect was present in both neonatal and postneonatal deaths.

Conclusions: Continuing reductions in SO2 levels in the UK may yield additional health benefits for infants.

Abbreviations: df, degrees of freedom; PM₁₀, particulate matter <10 µg/m³

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