Research report
Time series analysis of air pollution and mortality: effects by
cause, age and socioeconomic status
Nelson Gouveiaa, Tony Fletcherb
a Departamento
de Medicina Preventiva, Faculdade de Medicina da Universidade de
São Paulo-FMUSP, Av Dr Arnaldo 455, Sao Paulo, 01246-903-SP,
Brazil, b London School of
Hygiene and Tropical Medicine, London
Correspondence to: Dr Gouveia (ngouveia{at}usp.br)
Accepted for publication 4 May 2000
OBJECTIVE
To
investigate the association between outdoor air pollution and mortality
in São Paulo, Brazil.
DESIGN
Time series
study
METHODS
All causes,
respiratory and cardiovascular mortality were analysed and the role of
age and socioeconomic status in modifying associations between
mortality and air pollution were investigated. Models used Poisson
regression and included terms for temporal patterns, meteorology, and autocorrelation.
MAIN RESULTS
All
causes all ages mortality showed much smaller associations with air
pollution than mortality for specific causes and age groups. In the
elderly, a 3-4% increase in daily deaths for all causes and for
cardiovascular diseases was associated with an increase in fine
particulate matter and in sulphur dioxide from the 10th to the 90th
percentile. For respiratory deaths the increase in mortality was higher
(6%). Cardiovascular deaths were additionally associated with levels
of carbon monoxide (4% increase in daily deaths). The associations
between air pollutants and mortality in children under 5 years of age
were not statistically significant. There was a significant trend of
increasing risk of death according to age with effects most evident for
subjects over 65 years old. The effect of air pollution was also larger
in areas of higher socioeconomic level.
CONCLUSIONS
These
results show further evidence of an association between air pollution
and mortality but of smaller magnitude than found in other similar
studies. In addition, it seems that older age groups are at a higher
risk of mortality associated with air pollution. Such complexity should
be taken into account in health risk assessment based on time series studies.
Keywords: air pollution; mortality; socioeconomic status
© 2000 by Journal of Epidemiology and Community Health
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